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Colorectal cancer has a backup plan, and it begins when mature gut cells regain stem-like traits
In a recent study, Stevens researchers have shown how colorectal cancers can evolve from mature intestinal cells that revert to stem cells. These findings explain why colorectal cancers are so ...
When inflammation damages the intestinal lining, differentiated enterocytes and crypt base columnar stem cells (CBCs) revert to a regenerative, fetal-like state and form revival stem cells (revSCs).
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